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真核细胞翻译起始因子(eukaryotic initiation factor 4E,eIF-4E)是一个25 kDa的蛋白复合物,在蛋白质合成的起始阶段起重要的调控作用。近年来研究发现eIF-4E的表达与肿瘤的发生发展有关,被认为是一种原癌基因和有价值的肿瘤标志物。本文就eIF-4E与口腔癌的关系作一综述。
Eukaryotic initiation factor 4E (eIF-4E) is a 25 kDa protein complex that plays an important regulatory role in the initial stage of protein synthesis. In recent years, the study found that the expression of eIF-4E associated with the occurrence and development of the tumor, is considered a protooncogene and a valuable tumor marker. This article reviews the relationship between eIF-4E and oral cancer.