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目的 通过观察昏迷患儿临床转归情况，探讨纳络酮对昏迷患儿的治疗作用。方法 各种原因引起的昏迷患儿８２ 例随机分成治疗组（ｎ＝４２）及对照组（ｎ＝４０），对照组给予常规抗感染、利尿脱水、降温镇静等治疗，治疗组在上述治疗基础上加用纳络酮。结果 治疗组的总有效率为５９ ．５ ％ ，对照组为４５ ％ ，差异有显著性（Ｐ＜ ０．０５）；治疗组住院天数较对照组缩短（治疗组１３ ．７±２．１５ｄ，对照组１５．８±２．０５ｄ，Ｐ＜０．０５）。结论 纳络酮治疗昏迷病人有较好疗效，可缩短平均住院日。
Objective To observe the clinical outcome of coma in children and explore the therapeutic effect of naloxone on children with coma. Methods 82 cases of coma caused by various causes were randomly divided into treatment group (n = 42) and control group (n = 40). The control group was given routine anti-infective, diuretic dehydration, Addition of naloxone on. Results The total effective rate of the treatment group was 59. 5% in the control group and 45% in the control group, the difference was significant (P <0.05). The hospitalization days in the treatment group were shorter than those in the control group (13.7 ± 2.15 days in the treatment group and 15.8 ± 2.05 days in the control group, P <0.05). Conclusion Naloxone treatment of coma patients have a good effect, shorten the average length of stay.