论文部分内容阅读
目的:探讨逼尿肌活动低下(DU)在下尿路症状(LUTS)患者中的流行病学现状、临床特征及诊疗策略。方法:回顾性分析了我院1 019例排除神经源性膀胱及解剖结构异常的LUTS患者的尿流动力学检查结果及随访资料,探讨DU在LUTS中的流行病学及临床诊治特点,并对106例DU患者治疗前后行尿流动力学检查,结合文献进行临床分析。结果:在就诊患者中,储尿期症状最为多见,在男性患者中,排尿期症状稍多于储尿期症状,而女性患者储尿期症状明显多于排尿期症状。男性患者中膀胱出口梗阻(BOO)的患者为57.9%,而女性患者中压力性尿失禁(SUI)患者达到了43.3%。27.4%男性及23.2%女性诊断为DU,男性及女性患病率差异无统计学意义。DU患者与非DU患者的临床表现无明显差异,均以LUTS为主要表现。DU可能合并有逼尿肌过度活动或BOO。DU随着年龄的增加,患病率逐渐增加。106例DU患者经治疗后行尿动力学检查发现逼尿肌收缩力有一定提高,治疗前后逼尿肌肌力差异有统计学意义。结论:DU是LUTS患者的常见病因,并有可能同时合并有逼尿肌过度活动或BOO。目前针对DU患者的治疗有一定效果。
Objective: To investigate the epidemiological status, clinical features and diagnosis and treatment strategies of detrusor activity (DU) in patients with lower urinary tract symptoms (LUTS). Methods: A retrospective analysis of our hospital 1 019 cases of excisional neurogenic bladder and anatomical abnormalities in patients with LUTS urodynamic findings and follow-up data to explore DU in LUTS epidemiology and clinical diagnosis and treatment characteristics, and 106 Cases of DU patients before and after treatment of urodynamic examination, combined with the literature for clinical analysis. Results: The symptoms of urinary storage were the most common among the visiting patients. In male patients, the symptoms of urination were slightly more than the symptoms of urinary storage while the symptoms of urinary storage were significantly more in female patients than those in urination. 57.9% of patients had bladder outlet obstruction (BOO) in men, compared with 43.3% of women with stress urinary incontinence (SUI). There was no significant difference in the prevalence of DU among 27.4% males and 23.2% females. There was no significant difference in clinical manifestations between DU patients and non-DU patients, all of which were mainly LUTS. DU may have detrusor over activity or BOO. DU increased with age, the prevalence increased. 106 cases of DU patients after treatment urodynamic examination found that detrusor contractility increased to a certain extent, before and after treatment of detrusor muscle strength was statistically significant. CONCLUSION: DU is a common cause of LUTS in patients and may be combined with detrusor over activity or BOO. Currently for the treatment of DU patients have a certain effect.