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目的:观察中西医结合治疗2型糖尿病并肺结核的临床疗效。方法:将60例气阴两虚型2型糖尿病并肺结核初治患者按就诊顺序随机分为2组各30例。对照组采用胰岛素、异烟肼、利福平、吡嗪酰胺、乙胺丁醇等治疗;治疗组在对照组治疗基础上加服益气养阴汤。2组均治疗30天为1疗程,1疗程后评定疗效。结果:肺部病灶好转率治疗组为83.3%,对照组为60.0%;痰菌阴转率治疗组为66.7%,对照组为36.7%;糖尿病疗效总有效率治疗组为90.0%,对照组为76.7%;以上3项指标2组分别比较,差异均有显著性意义(P<0.05)。治疗后,治疗组空腹血糖、餐后2h血糖与对照组比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。结论:益气养阴汤与西药联合治疗气阴两虚型2型糖尿病并肺结核初治患者,疗效优于单纯西药治疗。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of type 2 diabetes mellitus and pulmonary tuberculosis. Methods: Sixty patients with type 2 diabetes mellitus with deficiency of both qi and yin and type 2 diabetes mellitus and newly diagnosed pulmonary tuberculosis were randomly divided into two groups of 30 cases according to the order of their visits. The control group was treated with insulin, isoniazid, rifampicin, pyrazinamide and ethambutol. The treatment group was given Yiqi Yangyin Decoction on the basis of the control group. The two groups were treated for 30 days for a course of treatment, after a course of assessment of curative effect. Results: The improvement rates of lung lesions were 83.3% in the treatment group and 60.0% in the control group, 66.7% in the sputum negative conversion rate group and 36.7% in the control group, and 90.0% in the diabetic group and 90.0% in the control group 76.7% respectively. There was significant difference between the above three indexes in two groups (P <0.05). After treatment, the fasting blood glucose in the treatment group and the blood glucose in the postprandial 2h group were significantly different from those in the control group (P <0.05, P <0.01). Conclusion: Yiqi Yangyin Decoction combined with Western medicine in the treatment of patients with type 2 diabetes of qi and yin deficiency and initial treatment of pulmonary tuberculosis has better curative effect than western medicine alone.