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36 4对反复自发性流产夫妇中共检出染色体异常者 41例 ,占受检总数的 5 .6 3% ,共有 32种异常核型 ,其中染色体数目异常 11例 ,结构异常 30例 ,15例具有家族性遗传倾向 ,17例为新突变者。TORCH试验 ,女性组ToAbIgM、CMVAbIgM ,与对照组有显著性差异 (P <0 .0 5 )。 11对夫妇ABO、Rh血型不合 ,抗体滴度 >1:32。 3例女性具有生殖系统器质性病变。提示染色体异常、感染、血型不合、器质性病变与反复自发性流产相关。
36 4 pairs of recurrent spontaneous abortion, the Chinese Communist Party detected 41 cases of chromosomal abnormalities, accounting for 5.36% of the total number of subjects, a total of 32 abnormal karyotypes, including 11 cases of chromosomal abnormalities, structural abnormalities in 30 cases, 15 cases with Familial genetic predisposition, 17 cases of new mutations. TORCH test, female ToAbIgM, CMVAbIgM, and the control group were significantly different (P <0.05). 11 couples ABO, Rh blood group incompatibility, antibody titer> 1:32. Three women had reproductive system organic disease. Suggestive of chromosomal abnormalities, infections, blood group incompatibility, organic lesions and recurrent spontaneous abortion.