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目的探讨晚期腹盆腔恶性肿瘤(伴有腹腔积液)采用腹盆腔灌注化疗加BSD2000深部热疗的疗效及不良反应。方法 44例晚期腹盆腔恶性肿瘤患者随机分两组,联合治疗组22例,采用腹腔灌注化疗加BSD2000深部热疗;对照组22例,采用单纯腹腔灌注化疗。结果联合治疗组有效率为63.64%,对照组为31.81%,差异有统计学意义(P<0.01);两组不良反应除出汗(P<0.01)外,其余差异均无统计学意义(P>0.05)。联合治疗组治疗后生活质量较对照组治疗后提高(P<0.05)。结论 BSD2000S深部热疗并腹腔热灌注化疗适用于晚期腹盆腔恶性肿瘤伴腹腔积液,能够明显改善患者的生活质量。
Objective To investigate the efficacy and adverse reactions of peritoneal perfusion chemotherapy combined with BSD2000 deep hyperthermia in the treatment of advanced pelvic malignancies (with ascites). Methods Forty - four patients with advanced malignant tumors of the pelvic cavity were randomly divided into two groups. The combination therapy group (n = 22) received intraperitoneal chemotherapy and BSD2000 deep hyperthermia. The control group (n = 22) received simple peritoneal perfusion chemotherapy. Results The effective rate was 63.64% in the combined treatment group and 31.81% in the control group, the difference was statistically significant (P <0.01). There was no significant difference between the two groups except for sweating (P <0.01) > 0.05). The quality of life in the combined treatment group was significantly higher than that in the control group after treatment (P <0.05). Conclusion BSD2000S deep hyperthermia combined with intraperitoneal hyperthermic perfusion chemotherapy is suitable for advanced peritoneal malignancy with ascites, which can significantly improve the quality of life of patients.