消化性溃疡(简称“溃疡”)为一常见病,由于纤维胃镜的广泛使用,本病的确诊已非难事。除有严重并发症之外,绝大部分病人仅需内科治疗。除了注意休息、饮食、保暖等辅助措施外,药物是极重要的治疗手段。考虑到溃疡患者多数在基层医疗单位处理,本文拟着重谈国产溃疡治疗药,这些药物与国外同类产品相比,疗效和副反应均无差别。 1.H_2受体拮抗剂组织胺在胃液分泌中起着极为重要的作用,胃泌素和乙酰胆碱等要通过它的介导或调制才能发挥刺激胃酸分泌的作用,故壁细胞上的三大受体(组织胺_2(H_2)受体、毒蕈碱(M)受体、胃泌素(G)受体)中以H_2 Peptic ulcer (referred to as “ulcer”) is a common disease, due to the extensive use of fiber gastroscopy, the diagnosis of this disease is not difficult. Except for serious complications, most patients only need medical treatment. In addition to pay attention to rest, diet, warm and other ancillary measures, the drug is an extremely important treatment. Taking into account the majority of ulcer patients in primary care units to deal with, this article will focus on domestic ulcer treatment drugs, these drugs compared with similar foreign products, efficacy and side effects were no difference. 1.H2 receptor antagonist histamine plays an extremely important role in the secretion of gastric juice, gastrin and acetylcholine through its mediation or modulation can play a role in stimulating gastric acid secretion, so the parietal cells on the three major (Histamine-2 (H 2) receptor, muscarinic (M) receptor, gastrin (G) receptor)