报道了一种高原子经济性、高选择性合成β-羰基膦酸酯类化合物的催化水合体系.实验发现以廉价的Ag OAc作为催化剂,甲醇作为助催化剂,炔基膦酸酯顺利发生水合反应生成相应的目标产物,产率优秀.反应无需惰性气体保护,具有良好的官能团耐受性,杂环、卤素等官能团及杂环体系都对反应无明显影响. A highly economical and highly selective catalytic hydration system for β-carbonyl phosphonate compounds was reported.It was found that with the inexpensive Ag OAc as a catalyst and methanol as a co-catalyst, the alkynyl phosphonates were successfully hydrated The yield of the corresponding target product was excellent, the reaction did not need inert gas protection, and had good functional group tolerance. The functional groups and heterocyclic systems such as heterocyclic ring and halogen had no obvious effect on the reaction.