血管生成是近年来肿瘤研究的热点。血管的生成存在于很多病理生理过程,血管增殖的过程是受机体严格调控的。1945年Algire先提出了“肿瘤血管形成”的概念。肿瘤血管生成是指肿瘤细胞诱导的微血管生长以及肿瘤中血液循环建立的过程。研究肿瘤血管生成,不仅有助于了解肿瘤的发生 Angiogenesis is a hot topic in cancer research in recent years. The formation of blood vessels exists in many pathophysiological processes, the process of blood vessel proliferation is strictly regulated by the body. In 1945 Algire first proposed the concept of “tumor angiogenesis.” Tumor angiogenesis refers to the process by which tumor cells induce the growth of microvessels and the establishment of blood circulation in the tumor. Studying tumor angiogenesis not only helps to understand the occurrence of tumors