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复发性呼吸道感染的2岁以上儿童对23价肺炎球菌多糖（PS）菌苗不产生抗体应答,为此作者评价了含4、6B、9V、14、18C、19F和23F7个血清型的7价肺炎球菌PS-白喉毒素无毒性变种CRM_(197)结合菌苗在复发性呼吸道感染患儿中的免疫原性。参加本试验的儿童均有复发性呼吸道感染,都曾注射过DTP。为确定合适的接种人选,作者确定足够的IgG抗体应答是指免疫
The children over the age of 2 years with recurrent respiratory tract infection did not develop an antibody response to the 23-valent pneumococcal polysaccharide (PS) bacterin, and for this reason, the authors evaluated the 7 valency of 7 serotypes containing 4, 6B, 9V, 14, 18C, 19F and 23F Immunogenicity of pneumococcal PS-diphtheria toxin non-toxic variant CRM_ (197) in combination with bacterins in children with recurrent respiratory tract infection. Children who participated in the trial had recurrent respiratory infections and had received DTP. To determine the appropriate vaccination candidate, the authors determined that sufficient IgG antibody response means immunization