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试验目的:研究血管紧张素转换酶抑制剂对于长期微蛋白尿的胰岛素依赖性糖尿病患者发展到临床蛋白尿的速度及蛋白排泄率改变速度的影响。试验设计:在12个以医院为基础的糖尿病治疗中心进行了两年的随机、双盲、安慰剂对照的临床试验。患者对象:92名胰岛素依赖性糖尿病患
Objectives: To investigate the effect of angiotensin converting enzyme inhibitors on the development of clinical proteinuria and the rate of change of protein excretion in insulin-dependent diabetic patients with long-term microalbuminuria. Trial Design: A two-year randomized, double-blind, placebo-controlled clinical trial was conducted in 12 hospital-based diabetes treatment centers. Subjects: 92 insulin-dependent diabetic patients