,Protein microarray: A key approach of proteomics

来源 :生物学前沿 | 被引量 : 0次 | 上传用户:nwj9666
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Proteins are vital parts of living organisms,for they consist of the main components of physiological metabolic pathways.The expression and modification status of proteins in cells are time-and space-dependent based upon functions as well as responses to stress.A subject aiming at understanding of protein status under certain physiological condition in a large scale,termed proteomics,is fundamentally important in life science.Although the proteomic investigation mainly relies on electrophoresis,liquid chromatography,and mass spectrometry,protein microarray is emerging as one of new techniques,and its power is being recognized in the field recently.Herein,we highlight progress in protein microarray,both its generation and application.
其他文献
哲盟甜菜生产集中分布在西辽河两岸的冲积平原上,土质、气候等自然条件基本相同,耕作制度亦相近,均属井灌区。为了推广甜菜新品种,1987~1988年在甜菜生产区进行了甜菜品种引
籽粒硬度对谷物的加工品质具有重要影响,在众多的小麦族植物(尤其是小麦)中,籽粒的硬度性状主要由5D短臂上的Hardness(Ha)位点的两个主效基因,即Puroindoline a(Pina-D1)和Puroindoline b(Pinb-D1)控制,同时受基因Grain SoftnessProtein-1(Gsp-1)的影响。这三个基因所表达的蛋白(friabilin)分散在小麦胚乳内,它与淀粉
The information provided by completely sequenced genomes of methanogens can yield insights into a deeper molecular understanding of evolutionary mechanisms.This
Thyroid hormone receptors (TR),ligand-mediated transcription factors,regulate cell growth,differentiation,and apoptosis.In humans,two different genes encode TR-
多酚氧化酶(以下简称PPO)是高粱褐化的主要原因之一。PPO在植物的生长中起到重要的作用,具有重要的抗逆性,又影响食品的品质。但是关于高粱中SbPPO的分子信息却知之甚少。本研
Epigenetics has been becoming a hot topic in recent years.It can be mechanisms that regulate gene expression without changing DNA base sequence.In plants epigen
The Hedyotis diffusa Willd herbal compounds(HDWHCs)are commonly used as Chinese medicine to treat cancer patients with established clinical therapeutic efficacy
Emerging research has suggested that inflammatory stress may play a role in the development of obesity.Both the leptin and insulin receptor are sensitive to int
本文在以田间试验为依据,研究了不同密度和氮肥基追比例对超高产小麦烟农19号和西农979号产量和品质的调控效应。研究结果表明:1密度和氮肥运筹对超高产小麦产量的影响不同密度和氮肥基追比例对超高产小麦的产量均有明显的调节作用。适当密度,合理氮肥基追比例可以协调产量结构,显著提高小麦产量。烟农19和西农979均在中密度(基本苗300×104 hm-2)下,氮肥基追比例为5:5和4:6配置下,产量达到或较