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目的观察在社区门诊30例原发性高血压患者服用氯沙坦钾片降压作用的疗效以及该药对血生化的影响。方法给予患者服用治疗剂量的氯沙坦钾片达到正常稳定的血压水平,并在治疗前后对血钾、血钠、尿素氮、肌酐、肝功能进行检测。结果 30例原发性高血压患者经过定期的治疗观察,血压控制总有效率为96%;治疗前后血钾、血钠、尿素氮、肌酐、肝功能进行检测无明显变化。结论氯沙坦钾片对社区的原发性高血压患者治疗效果良好,对血钾、血钠、尿素氮、肌酐、肝功能无不良影响。
Objective To observe the effect of losartan potassium on blood pressure in 30 patients with essential hypertension in community outpatient clinic and the effect of this medicine on blood biochemistry. Methods Patients were given losartan potassium at the therapeutic dose to achieve normal and stable blood pressure levels, and serum potassium, serum sodium, urea nitrogen, creatinine and liver function were measured before and after treatment. Results Thirty patients with essential hypertension were treated regularly. The total effective rate of blood pressure control was 96%. There was no significant change in serum potassium, serum sodium, urea nitrogen, creatinine and liver function before and after treatment. Conclusion Losartan potassium tablets have good therapeutic effect on patients with essential hypertension in community and have no adverse effect on serum potassium, serum sodium, urea nitrogen, creatinine and liver function.