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目的：研究肾病患者的药物不良反应（ＡＤＲｓ） 发生率与患者性别、血型、年龄等的相关性。方法：应用药物流行病学的原理和方法，对住院患者的基本情况和用药情况、药物不良反应等进行记录、分析，用统计学方法探讨性别、血型、年龄等因素对ＡＤＲｓ 的影响。结果：Ａ 型、Ｂ 型、Ｏ 型及ＡＢ 型血患者的ＡＤＲｓ 发生率分别为１０－３ ％ 、１４－３ ％ 、１７ ％ 和３２ ％ ，ＡＢ 型与Ａ 型有显著性差异；女性的ＡＤＲｓ 发生率为１９ ％ ， 高于男性患者（１４ ％ ） ；不同年龄组的患者ＡＤＲｓ 发生率有显著差异； 有烟酒嗜好的患者略高于无此嗜好的患者。结论：性别、血型、年龄等因素均影响肾科病人ＡＤＲｓ 的发生率。
Objective: To study the correlation between the incidence of adverse drug reactions (ADRs) in patients with nephropathy and the gender, blood type, age and so on. Methods: The principles and methods of pharmacoepidemiology were used to record and analyze the basic situation, drug use and adverse drug reactions of inpatients. The statistical methods were used to explore the influence of gender, blood type and age on ADRs. Results: The incidence of ADRs was 10-3%, 14-3%, 17% and 32% in patients with type A, B, O and AB respectively. There was a significant difference between AD and A types The incidence of ADRs was significantly higher than that of male patients (19%). The incidence of ADRs in different age groups was significantly different. Patients with alcohol and tobacco preferences were slightly higher than those without such preferences. Conclusion: The gender, blood type, age and other factors all affect the incidence of ADRs in nephrology patients.