目的:研究并调查口服水杨酸盐同时给予水杨酸盐灌肠治疗对中轻度活动性溃疡性结肠炎患者来说优于单纯口服治疗。方法:对127例非卧床患者进行随机双盲对照研究。口服水杨酸盐公认剂量为每日4g(每日2次口服),疗程共8周。在前4周,所有患者额外接受睡前1g水杨酸盐或1g安慰剂保留灌 OBJECTIVE: To study and investigate the effect of salicylate in combination with salicylate orally on oral ulceration in patients with mild-to-moderate active ulcerative colitis. Methods: A randomized double-blind controlled study of 127 ambulatory patients. Salicylate is generally accepted oral dose of 4g (2 times a day orally) for a total of 8 weeks. In the first 4 weeks, all patients additionally received 1 g of salicylate or 1 g of placebo before going to bed