论文部分内容阅读
应用ABC免疫组化技术对42例周围神经肿瘤和滑膜肉瘤进行12种凝集素受体检测。结果:神经鞘瘤和神经纤维瘤PNA和RCA均阴性,恶性神经鞘瘤分别为55％和100％阳性。神经鞘瘤均表达PHA,30％表达LCA;神经纤维瘤均表达LCA,50％表达PHA。滑膜肉瘤15％表达RCA,85％表达WGA;恶性神经鞘瘤均表达RCA,不表达WGA。提示:PNA和RCA尤其RCA为鉴别周围神经肿瘤良恶性的标志。LCA和PHA为鉴别神经鞘瘤和神经纤维瘤的标志。RCA和WGA可作为鉴别恶性神经鞘瘤和滑膜肉瘤的标志。
Twenty-two cases of peripheral nerve tumors and synovial sarcoma were examined for 12 lectin receptors using ABC immunohistochemistry. Results: PNA and RCA were negative in both schwannomas and neurofibromas, and malignant schwannomas were 55% and 100% positive, respectively. The schwannomas expressed PHA and 30% expressed LCA. Neurofibromas expressed LCA and 50% expressed PHA. Synovial sarcoma 15% expressed RCA, 85% expressed WGA; malignant schwannomas expressed RCA, did not express WGA. Tip: PNA and RCA, especially RCA, are markers for the differentiation of benign and malignant peripheral nerve tumors. LCA and PHA are markers for the identification of schwannomas and neurofibromas. RCA and WGA can be used as markers to identify malignant schwannomas and synovial sarcomas.