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[Hochkeppel HK et al:Nature 291(5815):500,1981(英文)] 继Secher等1980年成功地分离了一株能产生鼠抗人IFN-α(Ly)单克隆抗体的杂交瘤细胞系,并将单克隆抗体首先用于干扰素的提纯之后,本文又报道建立了一株能持续稳定分泌鼠抗人成纤维细胞干扰素(IFN-β)单克隆抗体的杂交瘤细胞系。
[Hochkeppel HK et al: Nature 291 (5815): 500, 1981 (English)] Following Secher et al. In 1980 successfully isolated a hybridoma cell line that produces a murine monoclonal anti-human IFN- After the monoclonal antibody was first used for the purification of interferon, a new hybridoma cell line that can stably secrete monoclonal anti-human fibroblast interferon (IFN-β) monoclonal antibody was also reported.