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肝细胞色素 CYP2 C9催化一系列药物在体内的生物转化。CYP2 C9基因多态性形成的个体差异是相关药物代谢差异的主要原因 ,本文综述了 CYP2 C9基因的主要多态性类型在不同人群中的分布状况以及多态性与相关药物代谢的关系
Liver cytochrome CYP2 C9 catalyzes the biotransformation of a series of drugs in vivo. The individual differences in CYP2 C9 gene polymorphism are the main reasons for the differences in drug metabolism. In this review, we summarize the distribution of CYP2 C9 polymorphism in different populations and the relationship between polymorphism and drug metabolism