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目的观察国产和进口的奥美拉唑对于消化性溃疡出血患者的实际治疗效果及其成本—效果情况。方法选取消化性溃疡出血患者124例,随机分为国产组和进口组各62例,国产组使用国产奥美拉唑,进口组使用进口奥美拉唑,比较2组患者实际治疗效果及成本—效果情况。结果国产组治疗总有效率为93.55%,进口组治疗总有效率为95.16%,2组比较差异无统计学意义(P>0.05)。国产奥美拉唑药降价前和降价后的成本/疗效均优于进口奥美拉唑(P<0.05)。结论国产和进口奥美拉唑治疗消化性溃疡出血效果相当,但是国产奥美拉唑性价比更高,值得推广。
Objective To observe the actual treatment effect and the cost-effectiveness of domestic and imported omeprazole in patients with peptic ulcer bleeding. Methods 124 patients with peptic ulcer bleeding were randomly divided into domestic and imported groups of 62 cases, the domestic group using domestic omeprazole, imported group using imported omeprazole, the actual treatment effect and cost - Effect of the situation. Results The total effective rate of the domestic group was 93.55%, while the total effective rate of the imported group was 95.16%. There was no significant difference between the two groups (P> 0.05). Domestic omeprazole drug price and efficacy before and after price reduction are better than the imported omeprazole (P <0.05). Conclusion Domestic and imported omeprazole are effective in treating peptic ulcer bleeding, but domestic omeprazole is more cost-effective and worth promoting.