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目的了解广西河池市HIV/AIDS患者的隐孢子虫感染情况。方法选取2014年2月至2015年10月在广西河池人民医院就诊的HIV/AIDS患者258例作为调查对象,收集患者的粪便样本,采用改良-抗酸染色法检测隐孢子虫感染情况。结果共调查HIV/AIDS患者258例;其中98例患者接受抗逆转录病毒治疗;128例患者接受CD4+T细胞数检测,其中CD4+T细胞<200/mm~3患者88例,200/mm~3≤CD4+<400/mm~3患者20例,CD4+≥400/mm~3患者20例;伴有腹泻症状的患者86例,占33.33%;处于HIV感染的无症状期、获得性免疫缺陷综合征期(AIDS)的患者分别有146、112例。HIV患者感染途径主要为性接触。广西河池HIV/AIDS患者合并隐孢子虫的感染率为2.33%(6/258),伴有慢性腹泻HIV/AIDS患者合并隐孢子虫的感染率为6.98%(6/86)。结论广西河池市HIV/AIDS患者存在隐孢子虫合并感染情况,其流行特点有待进一步进行深入的调查。
Objective To understand the infection of Cryptosporidium in HIV / AIDS patients in Hechi, Guangxi. Methods A total of 258 HIV / AIDS patients treated in Hechi People’s Hospital of Guangxi from February 2014 to October 2015 were selected as the survey subjects. Stool samples were collected and the infection of Cryptosporidium was detected by modified-acid-fast staining. Results A total of 258 HIV / AIDS patients were investigated; 98 patients received antiretroviral therapy; 128 patients received CD4 + T cell count, of which 88 patients with CD4 + T cells <200 / mm ~ 3, 200 / mm There were 20 patients with ~ 3≤CD4 + <400 / mm ~ 3, 20 patients with CD4 + ≥400 / mm ~ 3, and 86 patients with diarrhea (33.33%). Asymptomatic HIV infection, acquired immune deficiency There were 146,112 patients with the syndrome (AIDS). The main route of HIV infection is sexual contact. The infection rate of Cryptosporidium parvum with HIV / AIDS in Hechi of Guangxi was 2.33% (6/258). The infection rate of Cryptosporidium with HIV / AIDS in patients with chronic diarrhea was 6.98% (6/86). Conclusion The prevalence of cryptosporidium parvum infection in HIV / AIDS patients in Hechi City of Guangxi Province is still unknown. The prevalence of cryptosporidiosis is yet to be further investigated.