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目的探讨Ａ型肉毒毒素对老年患者眼睑痉挛的疗效。方法对３８例老年病人进行眼睑多点注射Ａ型肉毒毒素治疗，以氯硝安定、安坦治疗３６例老年患者为对照。对两组治疗前后的病情分级、疗效进行比较。结果Ａ型肉毒毒素组和对照组的总有效率分别为１００％与４７．８％（Ｐ＜０．００１），显效率分别为９２．１％与２２．２％（Ｐ＜０．０５），Ａ型肉毒毒素明显优于对照组，且无全身不良反应，局部反应轻。结论Ａ型肉毒毒素为治疗老年患者眼睑痉挛的有效药物，且方法简便易行。
Objective To investigate the efficacy of botulinum toxin type A on eyelid spasm in elderly patients. Methods A total of 38 elderly patients underwent eyelid injection of botulinum toxin type A, and 36 elderly patients treated with clonazepam and antan were used as controls. The two groups before and after the treatment of grading, efficacy comparison. Results The total effective rates of botulinum toxin A group and control group were 100% and 47.8%, respectively (P <0.001), and the effective rates were 92.1% and 22.2% respectively (P <0.05 ), Botulinum toxin type A was significantly better than the control group, and no systemic adverse reactions, local reactions light. Conclusion Botulinum toxin type A is an effective drug for the treatment of blepharospasm in elderly patients, and the method is simple and easy to operate.