Synthesis and Crystal Structure of Methyl 3-(5-Bromo-1-ethyl-1H-indole-3-carbonyl)aminopropionate

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Methyl 3-(5-bromo-1-ethyl-1H-indole-3-carbonyl)aminopropionate has been syn-thesized by the acylation of 5-bromo-3-trichloroacetylindole with β-alanine methyl ester, followed by alkylation with ethyl iodide, in 82.6% yield. Its crystal structure was gotten and determined by Ⅹ-ray diffraction method. The crystal is of monoclinic, space group P2/c with a = 11.7927(8), b =14.9342(8), c=9.0060(5) A, β= 101.558(6)°, V= 1553.93(16) A,λ=0.71073 A,μ(MoKa) = 2.656 mm
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