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目的 :应用门电路核素心室显像及小剂量多巴酚丁胺 (DOB)负荷试验 ,对急性心肌梗死 (AMI)早期再灌注后左室舒张功能进行评价。方法 :指标采用高峰充盈率 (PFR)、平均充盈率 (MFR)、 1/ 3充盈率 (1/ 3FR) ,1/ 3充盈分数 (1/ 3FF)。结果 :DOB负荷前后 ,AMI组PFR、MFR、 1/ 3FR均显著低于对照组 (P <0 0 1及P <0 0 5 )。AMI组DOB负荷后上述指标均有一定程度的改善 (P <0 0 1)。结论 :AMI再灌注后左室舒张功能降低 ,而小剂量DOB负荷后可得到明显改善 ,表明缺血区域内存活心肌的贮备能被激活
Objective: To evaluate left ventricular diastolic function after early reperfusion of acute myocardial infarction (AMI) by using gate nuclide ventricular imaging and low-dose dobutamine (DOB) loading test. Methods: The indexes used were the peak filling rate, MFR, 1/3 filling rate and 1/3 filling fraction. Results: Before and after DOB, the PFR, MFR and 1 / 3FR in AMI group were significantly lower than those in control group (P <0.01 and P <0.05). AMI group DOB load after the above indicators have improved to some extent (P <0.01). CONCLUSION: Left ventricular diastolic function decreases after AMI reperfusion, but can be significantly improved after low-dose DOB loading, indicating that the reserve of viable myocardium in ischemic area can be activated