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目的:探讨临床治疗外感风热所致流行性感冒的制剂———复方银翘感冒颗粒的制备与质量控制方法。方法:处方中薄荷、荆芥及部分连翘药材提取挥发油,药渣再与其余药物加水煎煮,浓缩为浸膏,加入人工牛黄、糊精、蔗糖粉及乙醇适量,喷以挥发油,分装即得。采用薄层色谱法对方中荆芥、薄荷脑作定性鉴别,对绿原酸作含量测定。结果:该制剂组方合理,制备工艺可行,质量容易控制且稳定。结论:复方银翘感冒颗粒为纯中药复方制剂,安全有效,值得临床推广。
Objective: To investigate the clinical treatment of exogenous wind-heat caused by the preparation of influenza - compound Yinqiao cold particles preparation and quality control methods. Methods: prescription peppermint, Nepeta and some Forsythia herbs extract volatile oil, dregs and then the rest of the drug boiling water, concentrated extract, artificial bezoar, dextrin, sucrose powder and ethanol amount, spray with volatile oil, dispensing That is to say. Thin layer chromatography on the other side Nepeta, menthol for qualitative identification of chlorogenic acid for determination. Results: The preparation group was reasonable, the preparation process was feasible, the quality was easy to control and stable. Conclusion: Compound Yinqiao flu granules are pure traditional Chinese medicine compound preparation, safe and effective, worthy of clinical promotion.