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目的观察、评价老年高血压患者应用替米沙坦联合氨氯地平片治疗的效果。方法选择东营市东城医院2015年8月-2016年8月收治的老年高血压患者116例为研究对象,以随机数字表法分组,分为观察组和对照组各58例。观察组给予替米沙坦联合氨氯地平片治疗,对照组采用氨氯地平片治疗,共治疗8周,观察临床治疗效果及不良反应发生情况,对比治疗前、治疗4周、治疗8周时两组患者的收缩压及舒张压水平。结果观察组治疗前收缩压与舒张压水平、治疗后不良反应发生率均与对照组相近,差异无统计学意义(P>0.05);治疗后,与对照组比较,观察组临床疗效显著提高,收缩压、舒张压水平显著降低,差异有统计学意义(P<0.05)。结论临床治疗老年高血压过程中,应用替米沙坦联合氨氯地平片后,治疗效果能够明显提升,促使患者血压水平降低,并处于合理范围中,减少相关并发症发生风险,延长生存期。
Objective To observe and evaluate the effect of telmisartan and amlodipine in elderly hypertensive patients. Methods One hundred and sixteen elderly patients with hypertension in Dongcheng Hospital of Dongying City from August 2015 to August 2016 were enrolled in this study. The patients were randomly divided into observation group (58 cases) and control group (58 cases). The observation group was treated with telmisartan combined with amlodipine. The control group was treated with amlodipine for 8 weeks. The clinical effects and adverse reactions were observed. Before treatment, 4 weeks, 8 weeks after treatment Systolic and diastolic blood pressure in both groups. Results Before treatment, the systolic blood pressure and diastolic blood pressure in the observation group were significantly lower than those in the control group (P> 0.05). After treatment, compared with the control group, the clinical efficacy of the observation group was significantly improved, Systolic blood pressure and diastolic blood pressure decreased significantly, the difference was statistically significant (P <0.05). Conclusion In the treatment of elderly patients with hypertension, telmisartan combined with amlodipine can significantly improve the therapeutic effect, reduce the blood pressure and maintain a reasonable range, reduce the risk of complications and prolong the survival period.