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目的:探讨食管癌合并胃间质瘤(esophageal cancer complicated with gastric stromal tumor,ECGST)患者的临床病理特点及生存分析。方法:回顾性分析本院自2009年5月~2013年3月确诊的14例ECGST患者的临床病理资料,并对患者生存进行随访。结果:ECGST的发生率约为0.54%。患者主要以食管癌的临床表现而就诊,术前普通内镜、CT检查对胃间质瘤的漏诊率均为100%。14例均在术中发现胃间质瘤病灶结节。14例食管癌病灶大小平均为2.84 cm(0.5~6.0 cm),胃间质瘤的病灶大小平均为0.69 cm(0.4~1.8 cm),每例患者的间质瘤病灶大小均小于相应的食管癌病灶大小。食管癌TNM分期为0期2例、Ⅰ期2例、Ⅱ期6例、Ⅲ期4例,胃间质瘤的TNM分期均为IA期;分期晚于相应的胃间质瘤TNM分期。12例胃间质瘤为极低度危险性,其余2例为低度危险性。术后随访时间9~41个月,除1例患者死亡外,余下13例存活。结论:ECGST并非罕见,ECGST患者术前胃间质瘤易漏诊。ECGST合并的胃间质瘤,相对于对应的食管癌,存在肿瘤大小较小、TNM分期早等特点。
Objective: To investigate the clinicopathological features and survival of patients with esophageal cancer complicated with gastric stromal tumor (ECGST). Methods: The clinical and pathological data of 14 patients with ECGST diagnosed in our hospital from May 2009 to March 2013 were retrospectively analyzed. Survival was followed up. Results: The incidence of ECGST was about 0.54%. Patients with the main clinical manifestations of esophageal cancer treatment, preoperative general endoscopy, CT examination of gastric misdiagnosis rate of 100%. 14 cases were found in the operation of gastric stromal tumor nodules. The average size of lesions in 14 cases of esophageal cancer was 2.84 cm (0.5-6.0 cm). The average size of lesions in gastric stromal tumors was 0.69 cm (0.4-1.8 cm). The size of each stromal tumor was smaller than that of the corresponding esophageal cancer The size of the lesion. The TNM stage of esophageal carcinoma was stage 0 in 2 cases, stage Ⅰ in 2 cases, stage Ⅱ in 6 cases and stage Ⅲ in 4 cases. The TNM stage of esophageal cancer was stage IA, and the stage was later than the corresponding TNM stage. 12 cases of gastric stromal tumors were extremely low risk, and the remaining 2 cases were low risk. The follow-up time ranged from 9 to 41 months. Except for 1 patient, the remaining 13 patients survived. Conclusions: ECGST is not uncommon and preoperative diagnosis of gastric stromal tumors in ECGST is misdiagnosed. ECGST merger of gastric stromal tumors, relative to the corresponding esophageal cancer, there are smaller tumor size, TNM staging earlier characteristics.