肝纤维化是多种慢性肝病的共同病理基础与特征 ,表现为以胶原为主的肝脏细胞外基质 (ＥＣＭ )各成分合成增多 ,降解相对不足 ,过多沉积在肝内。若进一步发展引起肝小叶改建、假小叶与结节形成 ,则进入肝硬化。目前认为肝纤维化是可逆性病变 ,而肝硬化则不可逆转。但在实际工作 Liver fibrosis is the common pathological basis and characteristics of many chronic liver diseases. It is characterized by an increase in synthesis of various components of the extracellular matrix (ECM) of the liver, mainly collagen, which is relatively undegraded and excessively deposited in the liver. If further development caused by hepatic lobule remodeling, false lobules and nodules, then into cirrhosis. Liver fibrosis is currently considered reversible lesions, cirrhosis is irreversible. But in actual work