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观测室间隔的老年性改变，探讨其机制及临床意义。方法：取天津市高校健康教师２６３人，分成５个年龄组，行超声心动图检查。结果：（ １）室间隔与主动脉根部夹角与年龄呈负相关（ ｒ＝－ ０． ３０４， Ｐ＜ ０． ０１）。（２）室间隔“乙状形”改变：主动脉与室间隔连接处至心尖的距离（Ｄ）随增龄缩短（ｒ＝－ ０． ２９４， Ｐ＜ ０． ００１）；室间隔至Ｄ线的最大垂直距离与年龄呈正相关（ｒ＝０．１９，Ｐ＜０．０１）。结论：此“乙状形”改变可能与室间隔被长期血流冲击及扩张和伸长的主动脉向下推压室间隔有关。此形变可延长并改变左室射血血流轨迹，增加内摩擦力和射血阻力，从而降低左室射血效率。
Observation of septal senile changes to explore the mechanism and clinical significance. Methods: Totally 263 health teachers in colleges and universities in Tianjin were divided into five age groups for echocardiography. Results: (1) The angle between ventricular septum and aortic root was negatively correlated with age (r = - 0. 304, P <0.01). (2) The “sigmoid” changes of the interventricular septum: The distance from the apex to the apical septum (D) decreased with age (r = - 0.294, P <0.001) The maximum vertical distance was positively correlated with age (r = 0.19, P <0.01). CONCLUSIONS: This “sigmoid” change may be related to the interventricular septum being impacted by long-term blood flow and the dilatation and extension of the aortic depressions. This deformation can extend and change the trajectory of left ventricular ejection blood flow, increased internal friction and ejection resistance, thereby reducing the efficiency of left ventricular ejection.