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作者在5年内观察到慢性持续性肝炎(CPH)12例有持续性或间隙性非结合性胆红素血症(最高血清胆红素为2.1～3.6mg%),其中8例有血清转氨酶持续升高.这12例作血红蛋白、网织细胞计数、大便尿胆原测定无明显溶血现象.7例行放射标记红细胞存活期测定中6例正常。结果 12例非结合胆红素血症 CPH 的肝胆红素糖醛酸转换酶(UDPG-T)活性(单位=每克肝组织每小时结合毫克胆红素)为0.16～0.39u(平均±SEM=0.27±0.02)与正常者(23例)0.68～1.99μ(1.35±0.08)相比差别显著(P<0.001)。与急性病毒性肝炎(53例)0.78～2.28u(1.41±
In 5 years, the authors observed that 12 patients with chronic persistent hepatitis (CPH) had persistent or interstitial nonbinding bilirubin (the highest serum bilirubin was 2.1-3.6 mg%), of which 8 patients had serum aminotransferase Increased.The 12 cases of hemoglobin, reticulocyte count, urinary bile determination of hemolysis no obvious hemolysis.7 cases of radioactive labeled erythrocyte survival 6 normal. Results The UDPG-T activity (unit = milligrams of bilirubin per hour per gram of liver tissue) of 12 unconjugated bilirubin CPH was 0.16-0.39 u (mean ± SEM = 0.27 ± 0.02) were significantly different from those of normal controls (23 cases) (0.68 ~ 1.99μ, 1.35 ± 0.08) (P <0.001). And acute viral hepatitis (53 cases) 0.78 ~ 2.28u (1.41 ±