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目的对甲状腺患者诊断方法进行临床流行病学分析,评估各种诊断方法在分化型甲状腺癌诊断中的意义、优势,对临床合理使用这些方法提供参考。方法整理分析了2014年1月1日—12月31日期间因甲状腺疾病于青岛大学附属医院就诊并行手术切除治疗患者205例,依据术后常规病理结果作为金标准,分别对病史和触诊、超声、超声引导性细针穿刺活检、CT、术中快速冰冻病理诊断进行流行病学统计,运用四格表进行运算、分析和评价。结果病史和触诊、超声、超声引导性细针穿刺活检、CT、术中快速冰冻病理诊断甲状腺癌的灵敏度分别为78.95%、83.15%、88.67%、74.28%、99.47%,特异度分别为60%、75%、80%、71.4%、100%。结论目前对于分化型甲状腺癌的术前良、恶性诊断,缺乏有效和确切的手段,需要根据患者具体病情选用合理的诊断方法。
Objective To analyze the clinical epidemiology of thyroid patients and to evaluate the significance and advantages of various diagnostic methods in the diagnosis of differentiated thyroid cancer and to provide references for the clinical rational use of these methods. Methods A total of 205 patients with thyroid disease undergoing surgical resection in Qingdao Hospital Affiliated Hospital of Qingdao University from January 1, 2014 to December 31, 2014 were analyzed. According to the postoperative routine pathological results as the gold standard, the medical history and palpation, Ultrasound, guided fine needle aspiration biopsy, CT, rapid intraoperative frozen pathological diagnosis of epidemiological statistics, the use of four tables for computing, analysis and evaluation. Results The sensitivity of history and palpation, ultrasound, guided fine needle aspiration biopsy, CT and rapid intraoperative frozen pathology were 78.95%, 83.15%, 88.67%, 74.28% and 99.47%, respectively, and the specificity were 60 %, 75%, 80%, 71.4%, 100%. Conclusion Currently, there is a lack of effective and exact means for the diagnosis of differentiated thyroid cancer, which requires a reasonable diagnosis according to the specific condition of patients.