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测定４４例不同类型乙型肝炎患者外周血单个核细胞产生的白细胞介素６（ＩＬ－６）活性水平及其与血清抗肝细胞膜脂蛋白（ＬＳＰ）浓度、肝功能和乙肝病毒复制指标的关系。主要发现重型肝炎、慢活肝患者的ＩＬ－６活性水平和抗ＬＳＰ浓度明显增高（Ｐ＜０．０１），慢迁肝、急性肝炎患者则无明显改变（Ｐ＜０．０５），ＩＬ－６活性水平与抗ＬＳＰ浓度呈正相关（Ｐ＜０．０１）。ＩＬ－６活性水平与ＨＢＶ－ＤＮＡ及ＨＢｅＡｇ呈负相关（Ｐ＜０．０５）。
To determine the level of interleukin-6 (IL-6) produced by peripheral blood mononuclear cells in 44 patients with different types of hepatitis B and its relationship with serum anti-hepatocyte membrane lipoprotein (LSP) concentration, liver function and hepatitis B virus replication . The levels of IL-6 and anti-LSP were significantly increased in patients with severe hepatitis and slow-acting liver (P <0.01), those in chronic hepatitis and acute hepatitis were not significantly different (P <0.05) 6 activity was positively correlated with anti-LSP concentration (P <0.01). The level of IL-6 activity was negatively correlated with HBV-DNA and HBeAg (P <0.05).