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1985年平山县某村发生了甲肝流行,诊断检测时,1～15岁儿童未发现HBsAg 阳性,HBV 感染率也很低(2.6%)。为探讨HBV 低感染村的感染特征及因素,1988年调查了全村居民HBV 感染状况。现报告如下。调查方法全村居民检测HBV 标志,采血率96.6%(552/571),同时调查肝病史、医疗损伤史、注射史、妇女婚史等。凡HBsAg 阳性者及其家属HBV 阴性者,一年后复查HBV 标志。用北京生研所和北京生化免疫制剂中心的RiA 试剂。HBsAg 和抗-HBsS/N 值≥2.1为阳性,抗-HBc Co/S 值≥1.0为阳性。HBV 标志阳转者,将前一年阴性和本次阳性血清同时复测,结果一致定为新感染。
In 1985, a hepatitis A epidemic occurred in a village in Pingshan County. HBsAg was not found in children aged 1-15 years at a diagnostic test, and the HBV infection rate was also very low (2.6%). In order to investigate the characteristics and factors of infection in villages with low HBV infection, the status of HBV infection in the whole village was investigated in 1988. The report is as follows. Methods of investigation The whole village residents detected HBV markers, blood collection rate of 96.6% (552/571), while investigating the history of liver disease, medical history of injury, history of injection, the history of women’s marriage. Where HBsAg-positive and their families HBV-negative, one year after the review of HBV markers. With Beijing Institute of Biochemical and Beijing Biochemical Immune Agents Center RiA reagent. HBsAg and anti-HBs / N values ≥2.1 were positive, anti-HBc Co / S values ≥1.0 were positive. HBV markers positive person, the previous year negative and the positive serum at the same time retest, the result agreed as a new infection.