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目的分析纳洛酮联合氨茶碱治疗新生儿呼吸暂停的临床疗效。方法本院2009年1月-2013年1月新生儿呼吸暂停的患儿60例,随机分为两组,两组均给予常规治疗,对照组30例给予氨茶碱;研究组30例,在对照组基础上加用纳洛酮。观察比较两组患者的临床疗效。结果研究组的总有效率和显效率均明显高于对照组,差异具有统计学意义(P<0.05)。两组患者在不良反应发生率上差异无统计学意义(P>0.05)。结论纳洛酮联合氨茶碱治疗新生儿呼吸暂停取得较好的疗效,且不良反应少,临床上值得推广。
Objective To analyze the clinical efficacy of naloxone combined with aminophylline in the treatment of neonatal apnea. Methods 60 cases of neonatal apnea in our hospital from January 2009 to January 2013 were randomly divided into two groups, the two groups were given routine treatment, the control group, 30 cases were given aminophylline; the study group, 30 cases, Control group based on the use of naloxone. Observed and compared the clinical efficacy of two groups of patients. Results The total effective rate and markedly effective rate of the study group were significantly higher than that of the control group, the difference was statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Naloxone combined with aminophylline in the treatment of neonatal apnea to achieve better results, and fewer adverse reactions, clinically worth promoting.