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作者对762名巴西儿童(7～17岁)各种蠕虫病的疗效进行了观察。其中602人用Mebendazole(R-17.635)的各种疗法时均无任何副反应,疗效优于左旋四咪唑。R—17.635每次剂量为200毫克,每日2次,连服4天的治愈率:蛔虫感染为100%,鞭虫感染为96～100%,蛲史感染为100%,钩虫感染为84.2～100%,对粪类圆线虫感染无效(Folha Med,63(6):843,1971)。作者后又报道(Folha Med..64(1):139,1972)58名儿童(3～15岁)蠕虫感染者每天口服R-17.635次,每次100毫克,连服3天后的疗效亦很满意,蛔虫、蛲虫、鞭虫及钩虫感染的治愈率分别达100%、100%、92.3%及92.8%。服药后未见出现副反应。作者认为此药是目前治疗肠道蠕虫病最
The authors observed the effects of various helminthiasis on 762 Brazilian children (7-17 years old). Of these, 602 patients had no side effects with various treatments of Mebendazole (R-17.635), with superior efficacy over levamisole. R-17.635 per dose of 200 mg twice daily, even for 4 days the cure rate: roundworm infection was 100%, whipworm infection was 96 to 100%, history of infection was 100%, hookworm infection was 84.2 ~ 100%, infecting stink bug (Folha Med, 63 (6): 843, 1971). The authors later reported (Folha Med..64 (1): 139, 1972) 58 children (3-15 years) who were infected with helminths received R-17.635 oral doses of 100 mg daily for 3 days Satisfaction, roundworm, pinworm, whipworm and hookworm infection cure rates were 100%, 100%, 92.3% and 92.8%. No side effects after taking medicine. The author believes that this medicine is currently the most treatment of intestinal worm disease