气体作为血管造影的对比剂的探索可追溯到1个世纪以前。在尝试过不同的气体后,纯度为99.9%的二氧化碳(CO2)在20多年前成功地应用于血管造影。CO2与其他气体的不同之处在于能迅速溶解于血液内,不易产生气栓和对呼吸功能影响较小。在这漫长的探索中,虽未曾有高潮迭起的研究热潮, The exploration of gas as a contrast agent for angiography dates back more than a century. After trying out different gases, 99.9% purity of carbon dioxide (CO2) was successfully applied to angiography more than 20 years ago. The difference between CO2 and other gases is that it dissolves quickly in the bloodstream, is less likely to produce air plugs and has less effect on respiratory function. In this long exploration, although there has been no upsurge of research upsurge,