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用超高频测听法对用耳毒性药物的连续腹膜透析病人(CAPD)进行耳毒性监护。19例CAPD 病人均作 ENT 检查,包括治疗前常规纯音0.26~8kHz 和超高频10~20kHz 测听,治疗后间歇一周再测听。常规纯音测听用 Interaco-ustics AC 4型听力计和 TDH-39型耳机,超高频测听用丹麦 HF 听力计和附有瓷隔膜的动态耳机。万古霉素行腹膜内用药,25mg/次,一周或2周后改用负荷量500mg/次,庆大霉素5 mg/次,方法时间同万古霉素。规定血中药物浓度无毒性范围为万古霉素<50mg/次,庆
Ototoxicity monitoring of continuous peritoneal dialysis patients (CAPD) with ototoxic drugs using ultra-high frequency audiometry. 19 cases of CAPD patients were ENT examination, including the treatment of conventional pure tone 0.26 ~ 8kHz and ultra-high frequency 10 ~ 20kHz audiometry, intermittent treatment after a week and then listen. Conventional pure tone audiometry Interaco-ustics AC 4 type hearing aids and TDH-39 headphones, UHF audiometry with Danish HF audiometer and porcelain diaphragm with dynamic headphones. Vancomycin intraperitoneal administration, 25mg / time, one week or two weeks after the switch to load 500mg / time, gentamicin 5 mg / time, method time with vancomycin. Provisions for blood drug concentrations non-toxic range of vancomycin <50mg / times, celebrate