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【目的】探讨四维超声时空关联成像（spatio‐temporal image correlation ，STIC）在产前早期胎儿先天性心脏病筛选中的应用价值。【方法】选择经常规初筛的早期高危妊娠孕妇85例，由同一位经验丰富的医师依次采用二维（对照组）和STIC超声检查（观察组），分别记录诊断结果和操作时间，并将诊断结果与随访确诊结果对比，同时采用自制满意度调查表对所有孕妇进行满意度的问卷调查。【结果】观察组采集时间（48±13）min少于对照组（173±58）min ，且满意度也大于对照组。随访结果显示观察组误诊3例、漏诊3例，对照组误诊11例、漏诊6例；观察组灵敏度为86．96％（20／23），与对照组73．91％（17／23）比较无显著性差异（ P ＞0．05）；观察组特异性和准确度分别为95．16％（59／62）、92．94％（79／85），显著高于对照组82．26％（51／62）和80．00％（68／85），差异有统计学意义（ P ＜0．05）。【结论】STIC技术对产前胎儿先天性心脏病筛选有较高的灵敏度和准确度，同时可有效减少采集时间，提高孕妇满意度。“,”[Objective] To explore the application value of four‐dimensional ultrasound spatio‐temporal im‐age correlation (STIC) in prenatal screening of early fetal congenital heart disease .[Methods] The same expe‐rienced physician employed both 2‐dimensional (control) and STIC (observation) scans on a total of 85 early fetal cases .Diagnosis and operation time were recorded .And diagnostic and follow‐up results were compared with the relevant real‐time data .A self‐made questionnaire of Satisfaction Survey was administered for all pregnant women .[Results] The acquisition time was shorter in observation group than that in control group [(48 ± 13) vs(173 ± 58)min] .And the satisfaction level was greater in observation group .According to the follow‐up results ,the numbers of mistaken and missed diagnoses were 3 and 3 in observation group and 11 and 6 in control group .The sensitivity of observation group was higher than that of control group [86 .96% (20/23) vs 73 .91% (17/23)] .Yet there was no statistical difference ( P >0 .05) .The specificity and accuracy were 5 .16% (59/62) and 92 .94% (79/85) in observation group and were significantly higher than those in control group .The differences were statistically significant ( P < 0 .05) .[Conclusion] The application of STIC technology in prenatal screening for fetal congenital heart diseases has a high sensitivity and a high accu‐racy .And it can effectively reduce acquisition time .With a strong feasibility ,it is worthy of wider populariza‐tion .