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目的 探讨食管癌单纯放疗疗效及影响预后的因素。方法 回顾分析1985年7月至1989年9月期间根治性放疗139例食管癌的临床有关资料,采用Kaplan—meier法及Cox模型进行分析。结果 经放疗后的食管癌患者1、5、10年的生存率分别为76.6％、29.5％和11.5％。单因素分析显示,X线分型,病变长度及胸痛史等对生存期有影响,多因素分析影响预后因素为X线分型、病变部位、胸痛史、病变长度。结论 单纯性放疗对早中期食管癌可达到较好效果,病变位于胸上段或颈段,X线分型蕈伞或腔内型疗效好,胸下段溃疡型及缩窄型疗效差。
Objective To investigate the efficacy of radiotherapy for esophageal cancer and the factors that influence the prognosis. Methods The clinical data of 139 cases of esophageal cancer treated with radical radiotherapy from July 1985 to September 1989 were retrospectively analyzed. The Kaplan-Meier method and the Cox model were used for analysis. Results The survival rates of patients with esophageal cancer after radiotherapy at 1, 5, and 10 years were 76.6%, 29.5%, and 11.5%, respectively. Univariate analysis showed that X-ray classification, lesion length, and history of chest pain had an effect on survival. Multivariate analysis affected the prognostic factors of X-ray type, lesion location, chest pain history, and lesion length. Conclusions Simple radiotherapy can achieve good results in the early and middle stage of esophageal cancer. The lesions are located in the upper thoracic or cervical segments. The efficacy of X-ray segmental fistula or intraluminal type is good. The efficacy of the lower thoracic ulcer and narrowing is poor.