轻链病是骨髓瘤的一种,是由于浆细胞恶性增生所致。其特征为临床上有多发性骨髓瘤的表现,而在实验室检查中血清免疫球蛋白的量正常或减少,血清和尿中可出现轻链,轻链病约占全部多发性骨髓瘤的10％左右。其中多数为单克隆κ(kappa)型,少数为单克隆λ(lambda)型。单克隆κ型和λ型同时存在于患者血清和尿中的“双轻链病”甚为罕见,但已见有报道。我院发 Light chain disease is a myeloma, due to malignant hyperplasia of plasma cells. It is characterized by clinical manifestations of multiple myeloma, and laboratory tests in the amount of serum immunoglobulin normal or reduced, serum and urine can appear light chain, light chain disease accounts for about all of the multiple myeloma 10 %about. Most of them are of kappa type, and a few of them are of lambda type. The “double light chain disease”, in which both monoclonal κ and λ forms coexist in the serum and urine of patients, is rare, but it has been reported. Our hospital hair