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目的研究影响新疆维吾尔族人群缺血性脑卒中发生的危险因素。方法采用1∶1配对病例对照研究方法,对100例维吾尔族缺血性脑卒中首发病人及相匹配的100名健康对照进行调查,采用Epdata3.0建立数据库及SAS9.0统计软件进行分析,筛选缺血性脑卒中的危险因素。结果多因素Logistic回归分析结果显示,高文化程度(OR=0.26,95%CI=0.14～0.47)、休闲中中轻度活动(OR=0.05,95%CI=0.01～0.42)为缺血性脑卒中的保护因素;而患有高血压(OR=32.44,95%CI=4.39～239.99)、腰臀围比超标(OR=4.01,95%CI=1.19～13.45)及过去2个月经历负性生活事件(OR=12.97,95%CI=1.18～142.23)则为危险因素;血液中高白蛋白(OR=0.86,95%CI=0.75～0.99)及高密度脂蛋白(OR=0.32,95%CI=0.15～0.64)为保护因素。结论影响新疆维吾尔族人群缺血性脑卒中发生危险因素较多,其特异性危险因素有腰臀围比超标和过去2个月经历负性生活事件。
Objective To study the risk factors affecting the occurrence of ischemic stroke in Xinjiang Uygur population. Methods A matched case-control study was conducted on 100 patients with Uygur ischemic stroke and matched 100 healthy controls. Epdata 3.0 database and SAS 9.0 software were used to analyze and screen Risk factors for ischemic stroke. Results The multivariate logistic regression analysis showed that there was a significant difference between the high education level (OR = 0.26, 95% CI = 0.14-0.47), moderate activity in leisure (OR = 0.05,95% CI = 0.01-0.42) (OR = 32.44, 95% CI = 4.39-239.99), waist-to-hip ratio exceeded (OR = 4.01, 95% CI = 1.19-13.45) and negative in the past two months Life events (OR = 12.97, 95% CI = 1.18-142.23) were risk factors; high albumin (OR = 0.86, 95% CI = 0.75-0.99) and high density lipoprotein (OR = 0.32, 95% CI = 0.15 ~ 0.64) as a protective factor. Conclusion There are many risk factors for ischemic stroke in Xinjiang Uygur population. The specific risk factors are excessively high ratio of waist-hip ratio and negative life events in the past two months.