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在英国,治疗性流产多在妊娠12周内进行,吸宫方法虽较安全,但需要熟练操作,闭经8周后每延迟一周,吸宫的危险性增大约15～30%,因此药物流产成为人们关注的问题,前列腺素(PG)E用于闭经<7周妇女的流产率约90%,但50%妇女有呕吐、腹泻及腹痛等副作用;而抗孕药mifepristone(RU486)副作用比PG轻,但不全流产率高。本文对RU486和不同剂量的PG阴道栓(gemeprost)联合应用的效果和副作用进行观察。在爱丁堡皇家医院妇科门诊部,对120例闭经<56天妇女进行药物流产。年龄>18岁,无严重疾病史,无妊娠并发症,无先兆流产表现。将患者分为随机和非随机二组,各组再按PG阴道栓的剂量
In the United Kingdom, the treatment of abortion and more in the 12 weeks of pregnancy, although the safety of the suction method, but the need for skilled operation, a week after the amenorrhea for a week, the risk of aspiration increased by about 15 to 30%, so medical abortion became Concerns have been raised that prostaglandin (PG) E is used in about 90% of abortions in women <7 weeks after amenorrhea but that 50% of the women have side effects such as vomiting, diarrhea and abdominal pain, whereas side effects of mifepristone (RU486) , But not full abortion rate. In this article, the effects and side effects of RU486 and different doses of PG vaginal suppository (gemeprost) in combination were observed. In the Department of Gynecology and Outpatient, Royal Botanic Gardens, Edinburgh, medical abortion was performed on 120 women <56 days of amenorrhea. Age> 18 years, no history of serious illness, no complications of pregnancy, no threatened abortion. The patients were divided into random and non-randomized two groups, each group then press PG vaginal suppository dose