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检测１０１例高血压病患者血、尿β２一徽球蛋白（β２一ＭＧ）含量，同时测定ＢＵＮ、血Ｃｒ的水平．并与７８名正常人进行对照。结果；高血压各组血、尿β２一ＭＧ明显高于对照组（Ｐ＜０．００１），且随病期进展而逐渐升高趋势，其敏感性明显优于ＢＵＮ、Ｃｒ，提示血、尿β２一ＭＧ可作为判断高血压病早期肾损害的一种敏感而可靠的指标。
The serum and urinary β2-globin (β2-MG) contents in 101 patients with essential hypertension were detected, and the levels of BUN and blood Cr were measured simultaneously. And compared with 78 normal people. Results Compared with control group, the blood and urine β2-MG levels in hypertension group were significantly higher than those in control group (P <0.001), and gradually increased with the progression of disease. The sensitivity was significantly higher than that of BUN and Cr, suggesting that blood and urine β2 MG can be used as a sensitive and reliable indicator of early renal damage in hypertensive patients.