目的　评价 6种具有致突变作用的空气燃烧排放提取物的致肺癌作用。方法　用CD 1小鼠肺瘤生物测试方法 ,在小鼠断奶前处理受试物 3次 ,6个月后观察肿瘤的发生率和病理组织学改变。并以苯并芘作为阳性对照。结果　 6种具有突变作用的空气燃烧排放提取物均具有致肺癌作用 ,并呈剂量 效应关系 ,另外发现其致肺癌作用与其中是否含二氯甲烷无关 Objective To evaluate the carcinogenic effects of six kinds of air-burning exhaust extracts with mutagenicity on lung cancer. Methods CD1 mouse lung tumor bioassay method was used to treat the mice three times before weaning, and the incidence of tumor and histopathological changes were observed after 6 months. And benzopyrene as a positive control. Results The six kinds of air-combustion exhaust extracts with mutagenic effects all had lung-cancer effects and showed a dose-response relationship. In addition, they also found that the lung-cancer effect was irrelevant to whether they contained methylene chloride or not