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大量实验与临床研究表明,带瘤机体的免疫机能状态随肿瘤的发展而不断改变。探讨这个问题的规律和机理,对肿瘤发病学,肿瘤免疫学的理论与临床实践均有一定的意义。本文观察了615系小鼠于接种本室建立的遵医肿瘤755(ZM755)后,带瘤宿主脾细胞E玫瑰花环和EAC玫瑰花环反应的动态变化,发现随着肿瘤的不断增长,两者均明显地进行性抑制。现将结果扼要报告如下:
A large number of experiments and clinical studies have shown that the immune function of the tumor-bearing organism constantly changes with the development of the tumor. To explore the law and mechanism of this problem, it has a certain significance for the theory and clinical practice of tumor oncology and tumor immunology. In this study, we observed the dynamic changes of tumor-bearing host spleen cells E rosette rosette and EAC rosette rosette after inoculation of the established Compliance Tumor 755 (ZM755) in the 615-type mice. It was found that as tumors continue to grow, both Obviously progressive inhibition. The results are summarized below: