随着移植免疫研究和移植外科技术的发展,器官移植广泛应用于临床。然而,世界上都存在供体器官远远不能满足受者(患者)需要的问题。虽然异种移植有可能解决器官供应不足的问题,但从1905年法国医生Princeteau进行了世界上第一例临床异种移植手术开始,至今的所有异种移植实验或手术研究都因移植后的供体器官遭受严重的免疫排斥反应而失活,其中最主要的是异种移植超急性排斥反应 With the development of transplant immunology and transplantation surgery, organ transplantation is widely used in clinical practice. However, there are problems in the world that donor organs are far from meeting the needs of recipients (patients). Although xenotransplantation may solve the problem of insufficient supply of organs, from the French doctor Princeteau in 1905 the world’s first clinical xenotransplantation began, all the xenograft experiments or surgical studies to date are due to the donor organ after transplantation Severe immune rejection and inactivation, the most important of which is hyperacute rejection of xenotransplantation