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近年来随着免疫学诊断的迅速发展,有关矽肺免疫发病机制和免疫诊断的研究亦日益增多。近20年来国内外有关学者在这方面做了不少工作,但迄今尚未取得较确切的答案。在研究内容上,也多偏重于实验室研究和矽肺患者体液免疫及血清蛋白变化等方面,细胞免疫的内容则较少。关于煤矿矽肺患者此方面的研究报导则更少。为了进一步观察煤矿矽肺患者的细胞免疫、体液免疫及血清蛋白变化的情况,深入探讨矽肺免疫发病机制,进行了本调查研究。
In recent years, with the rapid development of immunological diagnosis, the research on the pathogenesis and immune diagnosis of silicosis is also increasing. In the past 20 years, many scholars at home and abroad have done a lot of work in this field, but so far no definite answer has been obtained. In the research content, but also more emphasis on laboratory research and silicosis in patients with humoral immunity and serum protein changes, etc., the content of cellular immunity is less. There are few reports on this area of patients with silicosis in coal mines. In order to further observe the cellular immunity, humoral immunity and serum protein changes in patients with silicosis in coal mine, the pathogenesis of silicosis was explored in depth and the investigation was carried out.