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目的探讨马来酸桂哌齐特治疗糖尿病周围神经病变患者的临床效果。方法选取2010年3月至2015年3月一汽总医院收治的368例糖尿病周围神经病变患者作为研究对象,按随机数字表法将其分为对照组和观察组,各184例。对照组患者给予红花注射液进行治疗,观察组采用马来酸桂哌齐特注射液进行治疗,比较两组患者的治疗效果和不良反应发生情况。结果观察组治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);两组患者的不良反应发生率差异无统计学意义(χ2=2.321,P>0.05)。结论马来酸桂哌齐特治疗糖尿病周围神经病变患者临床疗效明显,不良反应少。
Objective To investigate the clinical effect of cinepazide maleate in the treatment of diabetic peripheral neuropathy. Methods A total of 368 patients with diabetic peripheral neuropathy admitted from January 2010 to March 2015 in FAW General Hospital were enrolled and divided into control group and observation group according to random number table method, with 184 cases in each group. Patients in the control group were treated with safflower injection. The observation group was treated with cinepazide maleate injection. The treatment effect and adverse reactions of the two groups were compared. Results The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions between two groups (χ2 = 2.321, P> 0.05). Conclusion Cinepazide maleate in the treatment of diabetic peripheral neuropathy patients with obvious clinical efficacy, fewer adverse reactions.