论文部分内容阅读
应用ABC免疫组化方法标记10多种单克隆抗体,用常规石蜡切片对100例临床诊断为恶性淋巴瘤的病例进行了研究。结果证明,在石蜡切片中能对恶性淋巴瘤发生阳性反应。否认了以往认为抗淋巴细胞各种单克隆抗体仅能用于冰冻切片新鲜淋巴组织的论点,检出淋巴瘤81例(B细胞性71例、T细胞性10例),何杰金氏病9例。单克隆抗体MT-1、CUHL-1、对T细胞性淋巴瘤呈阳性反应,MB-1、MB-2、LN-2、LN-3、L-26对B细胞性淋巴瘤呈阳性反应。Leu-M_1对何杰金氏病的诊断可起相当大的作用。
A total of more than 10 kinds of monoclonal antibodies were labeled with ABC immunohistochemical method, and 100 cases of clinically diagnosed malignant lymphoma were studied by conventional paraffin sections. The results show that paraffin sections can be positive for malignant lymphoma. Denied the past that all anti-lymphocyte monoclonal antibodies can only be used for frozen section of fresh lymph nodes argument, detected in 81 cases of lymphoma (B cell 71 cases, T cell 10 cases), Hodgkin’s disease 9 example. Monoclonal antibodies MT-1, CUHL-1, positive for T cell lymphoma, MB-1, MB-2, LN-2, LN-3, L-26 positive for B cell lymphoma. Leu-M_1 may play a considerable role in the diagnosis of Hodgkin’s disease.