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目的 调查肾移植术后医院感染的相关因素。方法 分析 10 0例肾移植患者术后感染情况及危险因素。结果 有 80 %患者术后早期均发生了不同程度的多部位感染 ,主要病原菌为真菌、金葡菌、铜绿假单胞菌、大肠埃希菌、克雷伯菌等共 2 8种 137株 ,而感染主要与免疫抑制药物、反复多次介入操作、手术创伤以及抗生素不合理使用是肾移植术后感染和患者死亡的主要原因。结论 综合性预防及合理使用抗生素是确保移植肾成功的重要因素之一。
Objective To investigate the related factors of nosocomial infection after renal transplantation. Methods The postoperative infection and risk factors of 10 0 cases of renal transplantation were analyzed. Results 80% of patients had different degrees of multi-site infection in the early postoperative period. The main pathogens were 338, 288 strains of fungi, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella. Infections, mainly immunosuppressive drugs, repeated multiple interventions, surgical trauma, and unreasonable use of antibiotics are the major causes of post-renal transplant infection and patient death. Conclusion Comprehensive prevention and rational use of antibiotics is one of the important factors to ensure the success of renal transplantation.