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异紫堇定在动物实验中可以抗失血性休克,增加动脉血压,本研究采用家兔造成急性失血性休克,测定草药异紫堇定抗失血性休克条件下血浆MDA及红细胞膜脂质流动性的改变,结果显示失血性休克条件下红细胞膜脂质流动性明显降低(P<0.05),而异紫堇定可以增加失血性休克时红细胞膜脂的流动性,使其维持在正常水平(P>0.05),此文对该草药的抗休克机制进行了探讨。
Isoniazid in animal experiments can hemorrhagic shock, increased arterial blood pressure, this study rabbits caused by acute hemorrhagic shock, the determination of herbs anisoisidine anti-hemorrhagic shock plasma MDA and erythrocyte membrane lipid fluidity (P <0.05). The results showed that the fluidity of erythrocyte membrane lipids was significantly reduced in hemorrhagic shock (P <0.05), while the iso-violet porphyrin could increase the fluidity of membrane lipids in hemorrhagic shock and maintain it at normal level (P> 0.05). This article discussed the anti-shock mechanism of this herb.